Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pathophysiology of amoebiasis.

S L Stanley1

  • 1Depts Medicine and Molecular Microbiology, Washington University School of Medicine, St Louis, MO 63110, USA. sstanley@im.wustl.edu

Trends in Parasitology
|May 30, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Estimating gene signals from noisy microarray images.

IEEE transactions on nanobioscience·2008
Same author

Vaccines for amoebiasis: barriers and opportunities.

Parasitology·2007
Same author

Blockade of caspases inhibits amebic liver abscess formation in a mouse model of disease.

Infection and immunity·2001
Same author

Protective immunity to amebiasis: new insights and new challenges.

The Journal of infectious diseases·2001
Same author

Microbes and microbial toxins: paradigms for microbial-mucosal interactions. VI. Entamoeba histolytica: parasite-host interactions.

American journal of physiology. Gastrointestinal and liver physiology·2001
Same author

Shigella infection in a SCID mouse-human intestinal xenograft model: role for neutrophils in containing bacterial dissemination in human intestine.

Infection and immunity·2001
Same journal

Hidden diversity in Trichuris control.

Trends in parasitology·2026
Same journal

The second Cryptosporidium meeting: Edinburgh's parasite deep dive.

Trends in parasitology·2026
Same journal

Evolution of generalism under Muller's ratchet.

Trends in parasitology·2026
Same journal

Next generation in parasitology 2026: Connecting young parasitologists across Europe.

Trends in parasitology·2026
Same journal

Disrupted barriers, evolved risks: toward precision One Health in arthropod allergy.

Trends in parasitology·2026
Same journal

Unveiling malaria history using ancient genomes.

Trends in parasitology·2026
See all related articles

Entamoeba histolytica, an intestinal parasite, can destroy human tissue. Recent studies reveal how its trophozoites cause intestinal disease and liver abscess, highlighting inflammation and cell death in amoebiasis.

Area of Science:

  • Microbiology
  • Pathogenesis
  • Parasitology

Background:

  • Entamoeba histolytica is an intestinal protozoan parasite known for its ability to lyse human tissue.
  • Amoebiasis, the disease caused by E. histolytica, manifests as intestinal disease and liver abscess.

Purpose of the Study:

  • To summarize recent research on E. histolytica interactions with the human intestine and hepatocytes.
  • To elucidate the mechanisms of tissue destruction and parasite killing ability.
  • To discuss the roles of inflammation and programmed cell death in amoebiasis pathogenesis.

Main Methods:

  • Utilizing new models of E. histolytica infection.
  • Analyzing host-parasite interactions in intestinal and hepatic environments.
  • Reviewing recent scientific literature on E. histolytica pathogenesis.

Related Experiment Videos

Main Results:

  • New infection models have improved understanding of how E. histolytica causes intestinal disease and liver abscess.
  • Recent work illuminates the parasite's potent tissue-damaging capabilities.
  • Studies highlight the involvement of inflammation and programmed cell death in disease development.

Conclusions:

  • Recent advancements provide insights into the pathogenesis of amoebiasis.
  • Understanding E. histolytica's interactions with host cells is crucial for developing effective treatments.
  • Inflammation and programmed cell death are key factors in E. histolytica-induced pathology.