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Low-grade non-Hodgkin's lymphoma in a patient with systemic lupus erythematosus
T Robak1, E Robak, J Bartkowiak
1Department of Hematology; Medical University of Lódź, Copernicus Memorial Hospital, Poland. robaktad@psk2.am.lodz.pl
Leukemia & Lymphoma
|May 30, 2001
Abstract:
Coexistence of systemic lupus erythematosus (SLE) with low-grade non-Hodgkin's lymphoma (LGNHL) has been described occasionally in the literature with the potential pathogenetic role of monoclonal B CD5+/CD19+ cells. We report a case of LGNHL which developed 18 months after diagnosis of SLE. The monoclonal population of lymphocytes in the peripheral blood and bone marrow was CD5/CD19 negative but CD19/CD22 positive. The SLE responded well to treatment with prednisone and the course of the LGNHL was stable and cytotoxic treatment was not required.