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An underlying circannual rhythm in seasonal affective disorder?
A Wirz-Justice1, K Kräuchi, P Graw
1Centre for Chronobiology, Psychiatric University Clinic, Basel, Switzerland. anna.wirzjustice@unibas.ch
Chronobiology International
|May 31, 2001
Abstract:
A patient diagnosed with seasonal affective disorder (SAD) carried out prospective ratings of depression weekly for nearly a decade. A winter peak of depression and benzodiazepine intake was documented. However, over the years, the depressive episodes shifted toward spring in an apparent free-running circannual rhythm (periodogram peaks at 53 and 55 weeks). This patient may have an underlying seasonal propensity to depression no longer precisely entrained to environmental cues.