Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Endemic mycotic infections].

V Briand1, O Lortholary

  • 1Fédération de médecine interne maladies infectieuses et tropicales. Hôpital Avicenne Bobigny. olivier lortholary@avc.ap-hop-paris.fr

La Revue Du Praticien
|June 5, 2001
PubMed
Summary

Endemic mycoses, fungal infections from environmental fungi, are rising in HIV patients due to AIDS epidemics and travel. Diagnosis involves various methods, and treatment requires long-term antifungal therapy and prophylaxis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tuberculosis after allogeneic hematopoietic stem cell transplantation: a decade nationwide case-control retrospective study in low-incidence country.

Bone marrow transplantation·2026
Same author

Determinants of radiological patterns and severity in immunocompromised adults with Metapneumovirus infection.

Respiratory medicine·2024
Same author

[Pulmonary complications of Chronic Granulomatous Disease].

Revue des maladies respiratoires·2024
Same author

[Screening and prevention of toxic optic neuropathies due to anti-mycobacterium therapies: proposal of recommendations].

Journal francais d'ophtalmologie·2022
Same author

Cerebral aspergillosis in the era of new antifungals: The CEREALS national cohort study Nationwide CEREbral Aspergillosis Lesional study (CEREALS).

The Journal of infection·2021
Same author

Combined High-Dose Caspofungin and Liposomal Amphotericin B for Treatment of Azole-Resistant Cerebral Aspergillosis.

Antimicrobial agents and chemotherapy·2021

Area of Science:

  • Mycology
  • Infectious Diseases
  • Public Health

Background:

  • AIDS epidemics and increased intercontinental travel contribute to the rising incidence of endemic mycoses.
  • These fungal infections, caused by environmental dimorphic fungi, are frequent in HIV patients and can be an AIDS-defining illness.
  • Primary infections are often asymptomatic or present as flu-like illness, but dissemination can occur in immunocompromised individuals.

Purpose of the Study:

  • To review the epidemiology, clinical manifestations, diagnosis, and treatment of endemic mycoses in the context of HIV/AIDS.
  • To highlight the significance of these infections as an AIDS-defining criterion.

Main Methods:

  • Literature review of endemic mycoses (histoplasmosis, coccidioidomycosis, blastomycosis, penicilliosis) in endemic areas.
  • Analysis of diagnostic methods including direct examination, histology, cultures, and serologies.
  • Review of treatment strategies involving amphotericin B and azoles, and prophylaxis.

Main Results:

  • Endemic mycoses are increasingly prevalent in HIV-infected individuals, particularly in endemic regions.
  • Infections can disseminate to skin, CNS, and bones, or present as chronic pulmonary disease in immunocompromised hosts.
  • Diagnosis relies on a combination of microbiological and serological tests.

Conclusions:

  • Prompt diagnosis and long-term treatment with antifungals like amphotericin B and azoles are crucial for managing endemic mycoses in AIDS patients.
  • Life-time secondary prophylaxis is recommended to prevent relapse in individuals with AIDS.

Related Experiment Videos