[Genetic risk factors in ischemic cardiopathy]

Coronary artery disease is a complex disease, characterized by a myriad of interactions between environmental and genetic factors. There is a growing interest about the genetic components. This research field is rapidly growing, and could offer new diagnostic and therapeutic tools in a near future. This paper will focus on common variations in several candidate genes. They have been categorized into three groups, according to different pathophysiological mechanisms: 1) lipid metabolism; 2) hemostatic balance; 3) non-lipid metabolism.