[Reversed C.P.C. :Case of 14-year old girl with large abnormal cells in her bone marrow]
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Updated: Aug 17, 2026

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
1Department of Laboratory Medicine, Keio University School of Medicine.
Abstract:
A 14-year-old female was admitted to our institute with arthralgia of the left pelvis. Magnetic resonance image analysis revealed the presence of a low-density area in her left pelvis. Although the complete blood count was almost within normal ranges, large abnormal cells with a round-shaped multi-nucleus and abundant cytoplasm containing coarse basophilic granules were noted in her bone marrow smear. She was diagnosed with mastocytosis after laboratory examinations. Nine months later, after intensive chemotherapy, the patient died.

