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[Chronic arsenicism]
A M Bourgeais1, M Avenel-Audran, A Le Bouil
1Service de Dermatologie et Vénérologie, CHU, Angers.
Annales De Dermatologie Et De Venereologie
|June 8, 2001
Summary
Chronic arsenicism, a rare condition characterized by skin changes, was diagnosed in a patient with high arsenic levels found in his homemade wine. This case highlights the importance of considering arsenic exposure from environmental sources.
Area of Science:
- Toxicology
- Environmental Health
Background:
- Arsenic is a naturally occurring element with potential health risks upon chronic exposure.
- Chronic arsenic exposure can lead to arsenicism, often presenting with distinctive dermatological manifestations.
Observation:
- A 75-year-old diabetic male presented with diffuse hyperpigmentation and asthenia.
- Clinical diagnosis of chronic arsenicism was supported by elevated arsenic levels in biological samples.
Findings:
- Investigation revealed exceptionally high arsenic concentrations in the patient's homemade wine.
- The source was likely improper use of sodium arsenite-based fungicides in viticulture.
Implications:
- This case underscores the need to consider arsenicism even when rare, emphasizing cutaneous signs and exposure routes.
- Long-term follow-up is crucial for patients with chronic arsenicism due to arsenic's carcinogenic potential.