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Related Experiment Videos

[Liver transplantation and constrictive pericarditis].

P H Bernard1, P Le Metayer, B Le Bail

  • 1Centre de Transplantation Hépatique, Hôpital Pellegrin, Bordeaux.

Gastroenterologie Clinique Et Biologique
|June 8, 2001
PubMed
Summary

Constrictive pericarditis can cause refractory ascites, mimicking liver disease. A liver transplant recipient

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Area of Science:

  • Cardiology
  • Hepatology
  • Transplantation

Background:

  • A patient presented with refractory ascites initially diagnosed as cryptogenic cirrhosis.
  • The patient underwent a liver transplantation based on this initial diagnosis.

Observation:

  • Post-transplantation, liver biopsy revealed lesions suggestive of a post-sinusoidal shunt.
  • Cardiac origin of ascites was suspected 5 months after the liver transplant.
  • Elevated right intra-ventricular pressures confirmed the constrictive pericarditis diagnosis.

Findings:

  • The patient's refractory ascites was caused by constrictive pericarditis, not liver disease.
  • Vascular liver lesions, indicative of the cardiac issue, were misinterpreted as cirrhosis pre-transplant.

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Implications:

  • Highlights the importance of considering cardiac causes for ascites, even with apparent liver disease.
  • Emphasizes the diagnostic challenge in interpreting liver biopsy findings in complex cases.
  • Underscores the need for thorough cardiac evaluation in patients with unexplained ascites and liver dysfunction.