Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Colloidal processing of hydroxyapatite.

L M Rodríguez-Lorenzo1, M Vallet-Regí, J M Ferreira

  • 1Departamento de Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Universidad Complutense de Madrid, Spain.

Biomaterials
|June 9, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From bone replacement to regeneration. A biomaterials started journey.

Materials today. Bio·2026
Same author

The burden of Wilson's disease: Insights into clinical, psychological, and functional dimensions.

Rehabilitacion·2025
Same author

Anti-inflammatory and antibacterial hydrogel based on a polymerizable ionic liquid.

Acta biomaterialia·2025
Same author

New materials and complications of prostheses in humans: situation in Spain.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2024
Same author

Antibiotic delivery from bone-targeted mesoporous silica nanoparticles for the treatment of osteomyelitis caused by methicillin-resistant Staphylococcus aureus.

Acta biomaterialia·2022
Same author

Injectable mesoporous bioactive nanoparticles regenerate bone tissue under osteoporosis conditions.

Acta biomaterialia·2022
Same journal

Corrigendum to "Enhanced fluorescence imaging guided photodynamic therapy of sinoporphyrin sodium loaded graphene oxide" [Biomaterials 42 (2015) 16442].

Biomaterials·2026
Same journal

An injectable Ce-MnCo LDH nanozyme gel with cascade catalytic activity for acute radiation proctitis in rats.

Biomaterials·2026
Same journal

Peptide coacervate-mediated siRNA delivery for dual PD-1/PD-L1 blockade to enhance colorectal cancer immunotherapy.

Biomaterials·2026
Same journal

A sonosensitizing hydrogel with tumour-confined stability for intrinsically targeted sonodynamic therapy.

Biomaterials·2026
Same journal

Multidimensional intestinal barrier repair strategies for alleviating inflammatory bowel disease and gut-liver axis-associated metabolic liver disease.

Biomaterials·2026
Same journal

A dual-twisted molecular strategy achieves dramatic quantum-yield enhancement in NIR-II AIEgen for high-performance bioimaging.

Biomaterials·2026
See all related articles

Advanced ceramic processing for implants requires optimizing hydroxyapatite (OHAp) powder. Ball milling and careful dispersant selection, like Targon 1128, improve suspension properties and final ceramic density.

Area of Science:

  • Biomaterials Science
  • Ceramics Engineering
  • Materials Science

Background:

  • Bioceramics are essential for medical implants due to their biocompatibility.
  • Hydroxyapatite (OHAp) is a key bioceramic, but its processing requires careful control.
  • Achieving optimal properties for implant devices necessitates advanced ceramic manufacturing techniques.

Purpose of the Study:

  • To investigate processing steps for advanced bioceramics for implant devices.
  • To evaluate the effect of heat treatment temperature on precipitated hydroxyapatite (OHAp) powder characteristics.
  • To optimize colloidal processing of OHAp for enhanced implant material properties.

Main Methods:

  • Precipitated hydroxyapatite (OHAp) powder was synthesized and subjected to heat treatment.

Related Experiment Videos

  • Calcined powders underwent 20-hour ball milling to enhance rheological properties.
  • Dispersing agents were screened using zeta potential and rheological measurements.
  • Slip-casting performance was evaluated for suspensions with varying solids loading.

    • Main Results:

    • Heat treatment temperature influenced OHAp powder's specific surface area, crucial for colloidal processing.
    • Ball milling significantly improved suspension rheology and powder packing.
    • Targon 1128 proved to be the most effective dispersant.
    • Fluid suspensions with 50 vol% solids were achieved using Targon 1128, yielding high green and sintered densities.

    Conclusions:

    • Optimized processing, including ball milling and dispersant selection, is critical for advanced bioceramic manufacturing.
    • Targon 1128 enables the preparation of high-solids loading OHAp suspensions.
    • The developed processing route leads to superior green and sintered densities for OHAp-based implant materials.