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Updated: Aug 17, 2026

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
Published on: September 19, 2013
[Sarcomatoid carcinoma of the prostate]
A Benchekroun1, M Zannoud, M Ghadouane
1Clinique Urologique A, Hôpital Avicenne, Rabat, Maroc. benchek.@mtds.com
Abstract:
The authors report a case of sarcomatoid carcinoma of the prostate in a 49-year-old patient. The clinical symptoms were dominated by dysuria and frequency. Digital rectal examination showed a very large, hard and irregular prostate. Serum PSA was normal. Transrectal ultrasonography and abdominopelvic computed tomography showed a heterogeneous mass occupying the vesico-prostatic junction. The patient underwent cystoprostatectomy. Histological examination of the cystoprostatectomy specimen revealed a tumour composed of spindle cells expressing epithelial markers on immunohistochemical analysis and concluded on a diagnosis of sarcomatoid carcinoma of the prostate. The patient died seven months after cystoprostatectomy.
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