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Updated: Feb 6, 2026

Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction
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Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction

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[Recent myocardial infarction and heart wall rupture: analysis of 21 cases surgically treated]

G Barboso1, C Cavozza, I Spaggiari

  • 1Cattedra di Cardiochirurgia, Università degli Studi di Sassari.

Acta Bio-Medica De L'Ateneo Parmense : Organo Della Societa Di Medicina E Scienze Naturali Di Parma
|June 14, 2001
PubMed

Insights

Prompt surgical repair of left ventricular free wall rupture after acute myocardial infarction can yield good long-term survival, despite high initial hospital mortality. Early diagnosis and assessment of infarct size are crucial for successful outcomes.

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Surgery Outcomes
  • Myocardial Infarction Complications

Context:

  • Left ventricular free wall rupture is a life-threatening complication of acute myocardial infarction.
  • Prognosis is heavily influenced by diagnostic speed, infarct size, and surgical intervention timeliness.

Purpose:

  • To evaluate the efficacy and long-term outcomes of emergency surgical repair for left ventricular free wall rupture.
  • To analyze factors influencing survival rates in patients undergoing surgical treatment.

Summary:

  • Twenty-one patients with left ventricular free wall rupture underwent emergency surgery between 1984 and an unspecified date.
  • Surgical techniques involved myocardial resection and repair using reinforced sutures or patching materials, with associated cardiac procedures performed as needed.
  • Hospital mortality was 33%, with prolonged postoperative courses requiring intensive care and support in several patients.

Impact:

  • Despite high hospital mortality, surgical repair in emergency settings can achieve satisfactory long-term survival.
  • Prompt diagnosis via echocardiography and accurate infarct size assessment are critical determinants of successful surgical outcomes and patient survival.

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