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Updated: Jul 17, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

Induction of HSP70 promotes DeltaF508 CFTR trafficking

L R Choo-Kang1, P L Zeitlin

  • 1Eudowood Division of Pediatric Respiratory Sciences, Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287-2533, USA.

American Journal of Physiology. Lung Cellular and Molecular Physiology
|June 19, 2001
PubMed
Summary

Heat shock protein 70 (HSP70) induction promotes the maturation and trafficking of the DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) mutant protein. This finding offers potential therapeutic strategies for cystic fibrosis.

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