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Related Experiment Videos

Penile pemphigus.

N Sami1, A R Ahmed

  • 1Department of Oral Medicine and Diagnostic Sciences, Harvard School of Dental Medicine, 188 Longwood Ave, Room I-217, Boston, MA 02115, USA.

Archives of Dermatology
|June 19, 2001
PubMed
Summary
This summary is machine-generated.

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Pemphigus vulgaris rarely affects penile skin, typically appearing with lesions elsewhere on the body. Penile involvement, often on the glans, resolved with treatment and showed no long-term issues.

Area of Science:

  • Dermatology
  • Autoimmune Diseases

Background:

  • Pemphigus vulgaris rarely involves penile skin.
  • This study investigates penile skin manifestations in 12 pemphigus vulgaris patients.

Purpose of the Study:

  • To describe the clinical characteristics and outcomes of penile skin involvement in pemphigus vulgaris.
  • To assess the frequency and presentation of penile lesions in pemphigus vulgaris.

Main Methods:

  • Retrospective analysis of 12 pemphigus vulgaris patients with penile skin involvement.
  • Serological testing for antibodies to keratinocyte cell surface antigens.
  • Clinical evaluation of lesion location and response to therapy.

Main Results:

  • Penile skin involvement occurred in 10 of 12 patients, often alongside other cutaneous and mucous membrane lesions.

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  • Lesions were most frequently observed on the glans penis.
  • No isolated penile skin involvement or urethral involvement was noted.

    • Conclusions:

    • Penile skin involvement in pemphigus vulgaris is uncommon and associated with widespread disease.
    • Glans penis is the most common site for penile lesions.
    • Treatment led to resolution without recurrence or long-term functional abnormalities.