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Updated: Aug 8, 2026

Impression Cytology of the Lid Wiper Area
Published on: August 9, 2016
[A clear cell type meningioma in the upper eyelid ascertained by immunohistochemical examination]
S Harada1, D Watanabe, H Kaneko
1Department of Ophthalmology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan.
Background:
We encountered a rare case of clear cell meningioma in the upper eyelid.
Case:
A 66-year-old man presented with a slow by progressive, well-defined, soft globelar tumor in the left upper eyelid. The tumor showed homogeneous isodensity and was contrasty in a computed tomograph. Histologically, oval-shaped cells with clear cytoplasm had both streamed and whorl configurations, but showed neither psammomas nor calcification. Immunohistochemically, vimentin, epithelial membrane antigen, and protein S-100 were expressed by the tumor cells.
Conclusions:
Eyelid meningioma may originate from embryonal remains of the arachnoid in the sheath around the trigeminal nerve, and may vary histologically. Immunohistochemical examination helps to define cases of uncommon subtypes of meningioma.
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