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Updated: Oct 7, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
[Pulmonary hypertension in patients with congenital and acquired heart diseases]
1Section of Cardiology, Department of Medicine, Tokai University School of Medicine.
Abstract:
Pathophysiology of pulmonary hypertension in patients with congenital and acquired heart diseases are described. The broken down of the pulmonary hypertension is left ventricular dysfunction and/or left atrial overloading, and high blood flow in pulmonary circuit with intra-cardiac or intra-vascular shunt. There are pulmonary venous, reactive, and arterial hypertension, related with the mechanism. The worsening of pulmonary venous hypertension induces acute hemodynamic pulmonary edema. The high blood flow in the pulmonary circulation due to large shunt develops Eisenmenger syndrome related with aging.
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