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Published on: September 26, 2018
Prevalence and Treatment of Hypertension Complicated by Comorbid Conditions
Joy L. Meier1, Julio Lopez, David Siegel
1Pharmacy Service Department of Veterans Affairs, Northern California Health Care System, Martinez, CA and School of Pharmacy, University of the Pacific, Stockton, CA.
Insights
Comorbid conditions like heart disease and diabetes are common in hypertensive patients, yet they rarely influence the choice of blood pressure medication. Most patients receive calcium antagonists or ACE inhibitors regardless of other health issues.
Area of Science:
- Cardiology
- Pharmacology
- Public Health
Background:
- Comorbid conditions are prevalent in patients with hypertension.
- The impact of these conditions on antihypertensive prescribing patterns is not well-understood.
- Understanding these factors is crucial for optimizing patient care.
Purpose of the Study:
- To determine the prevalence of comorbid conditions in hypertensive patients.
- To investigate whether comorbid conditions influence antihypertensive prescribing.
- To analyze prescribing patterns for common antihypertensive agents.
Main Methods:
- Retrospective analysis of 7526 patients receiving antihypertensive medication.
- Data collected from four Department of Veterans Affairs clinics.
- Prevalence of coronary artery disease (CAD), diabetes mellitus (DM), COPD/asthma, and congestive heart failure (CHF) assessed.
Main Results:
- High prevalence of CAD (33%), DM (32%), COPD/asthma (21%), and CHF (13%) noted.
- Comorbid conditions had minimal impact on antihypertensive agent selection.
- Calcium antagonists and ACE inhibitors were the most frequently prescribed agents.
- Beta-blocker use was not significantly influenced by the presence of CAD.
Conclusions:
- Current antihypertensive prescribing practices may not adequately account for comorbid conditions.
- Further research is needed to align treatment with patient complexity.
- Optimizing therapy based on comorbidities could improve outcomes for hypertensive patients.
Abstract:
Although the presence of a comorbid condition should be an important factor in etermining the choice of an antihypertensive agent, the prevalence of conditions complicating hypertension is unknown in most patient populations. It is also unknown whether the presence of comorbid conditions influences antihypertensive therapy. To address these questions, we determined the prevalence of comorbid conditions and antihypertensive prescribing patterns for 7526 patients receiving antihypertensive medication at four Department of Veterans Affairs clinics. Of these patients, 97% were male and 86% were over 50 years of age. In these hypertensives, 2507 had coronary artery disease (CAD), 2426 had diabetes mellitus (DM), 1553 had chronic obstructive pulmonary disease (COPD) or asthma, and 970 had congestive heart failure (CHF). The presence of comorbid conditions did not have a major impact on the choice of antihypertensive agents, with most hypertensives receiving calcium antagonists or ACE inhibitors. The use of à -blockers, for example, was not greatly influenced by the presence of CAD. (c)1999 by Le JacqCommunications, Inc.
Related Concept Videos
Hypertension and Regulation of Blood Pressure
Hypertension I: Introduction
Hypertension II: Pathophysiology
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension V: Nursing Management