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Measurement of mRNA Decay Rates in Saccharomyces cerevisiae Using rpb1-1 Strains
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Characterization of a general stabilizer element that blocks deadenylation-dependent mRNA decay

M J Ruiz-Echevarria1, R Munshi, J Tomback

  • 1Department of Molecular Genetics and Microbiology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey and the Cancer Institute of New Jersey, Piscataway, New Jersey 08854, USA.

The Journal of Biological Chemistry
|June 26, 2001
PubMed
Summary

Researchers identified a novel stabilizer element (STE) in the PGK1 gene, called P-STE. This element enhances mRNA stability by functioning within the translated region, suggesting a link between translation and mRNA decay in yeast.

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