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[Fetal lung maturity in biamniotic twin pregnancy]
J Piazze1, M Anceschi, T Marini
12o Istituto Clinica Ostetrica e Ginecologica, Università La Sapienza di Roma, Italia. jjpiazze2000@hotmail.com
Objective:
To assess the need to perform amniocentesis for the evaluation of fetal lung maturity (FLM) in both amniotic sacs of twin pregnancies.
Study Design:
A retrospective study. We considered 33 twin biamniotic pregnancies, delivering within 1 week from amniocentesis. FLM testing was performed by planimetric lecithin/sphingomyelin ratio (L/S), and lamellar bodies count (LB) according to our methodology.
Results:
A strong correlation was found between L/S (p < 0.001, r = 0.59) and LB (p < 0.001, r = 0.69) values between smaller and larger twins. No significant regression was found between differences of L/S and LB among both amniotic sacs against gestational age. When stratifying FLM values < 34 and > 34 wks' gestation, again no difference was found in mean difference of L/S and LB before and after 34 wks.
Conclusions:
FLM should not be assessed in both amniotic sacs at any gestational age independent of weight and/or sex of the conceptus.