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[CRIB score: mortality, morbidity, and long-term neurologic development].

A Coscia1, G Prandi, S Borgione

  • 1Cattedra di Neonatologia, Università di Torino. Coscia@pediatria.unito.it

Acta Bio-Medica De L'Ateneo Parmense : Organo Della Societa Di Medicina E Scienze Naturali Di Parma
|June 27, 2001
PubMed
Summary

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The Clinical Risk Index for Babies (CRIB) score effectively predicts mortality and major health issues in very low birth weight (VLBW) infants. Higher CRIB scores correlate with increased risks of mortality, chronic lung disease, retinopathy of prematurity, and neurodevelopmental impairment.

Area of Science:

  • Neonatology
  • Pediatric critical care

Context:

  • Very low birth weight (VLBW) infants face significant risks of mortality and long-term morbidities.
  • Accurate risk stratification is crucial for optimizing care and resource allocation in neonatal intensive care units.

Purpose:

  • To evaluate the predictive accuracy of the Clinical Risk Index for Babies (CRIB) score for mortality, major pathologies, and neurodevelopmental impairment in VLBW infants.
  • To analyze the association between CRIB score categories and specific adverse outcomes including mortality, chronic lung disease (CLD), retinopathy of prematurity (ROP), and neurodevelopmental impairment.

Summary:

  • A cohort of 251 VLBW infants was analyzed using the CRIB score, categorized into three risk groups (0-5, 6-10, >10).
  • Mortality rates significantly increased with higher CRIB scores (5.6% for 0-5, 32.4% for 6-10, 93.8% for >10).

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  • Incidence of severe ROP and CLD, as well as neurodevelopmental impairment at one and two years corrected age, also showed a positive correlation with increasing CRIB scores.

    • Impact:

    • The CRIB score demonstrates strong predictive power for mortality in VLBW infants.
    • The CRIB score is associated with an increased risk of severe ROP, CLD, and neurodevelopmental impairment, aiding in early identification of high-risk infants.
    • Findings support the use of the CRIB score for risk stratification and targeted interventions in VLBW neonates.