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A pendular mechanism for maintenance of the immune memory
V I Seledtsov1, G V Seledtsova
1Immunohematologic Department, Institute of Clinical Immunology, Novosibirsk, Russia. vs@online.nsk.su
Medical Hypotheses
|June 27, 2001
Abstract:
A possible mechanism for maintaining immune memory, based on idiotypic-anti-idiotypic interactions, is described. It is proposed that pendular dynamic swings in the levels of idiotypic antibodies (Ab1) and anti-idiotypic Ab2 may underlay immune memory. In the terms of the advanced concept, Ab dynamics in the maternal body might also play a significant role in education of the neonatal immune system.