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[Subcutaneous calcifications after radiotherapy].

M Steinert1, P Gottlöber, H Gall

  • 1Abteilung Dermatologie, Universitätsklinikum Ulm, Oberer Eselsberg 40, 89081 Ulm.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|June 29, 2001
PubMed
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This study reports a rare case of late-stage cutaneous radiation syndrome in a patient with cervical carcinoma. The patient developed a sacral abscess and subcutaneous calcifications, likely induced by radiotherapy received 32 years prior.

Area of Science:

  • Oncology
  • Radiotherapy
  • Dermatology

Background:

  • A 75-year-old female with a history of cervical carcinoma treated with radiotherapy 32 years prior presented with complications.
  • Late-stage effects of radiotherapy can manifest decades after treatment.

Observation:

  • The patient developed a deep abscess in the sacrum within the radiation-exposed area.
  • Imaging studies, including sonography and MRI, confirmed the abscess extending into subcutaneous fibrosis.

Findings:

  • Intravenous cefotiam treatment led to clinical and radiological improvement of the inflammation.
  • A secondary, unusual finding was distinctive subcutaneous calcification in the irradiated area, diagnosed via sonography, CT, and MRI.

Implications:

Related Experiment Videos

  • This case highlights the potential for delayed complications, such as abscesses and subcutaneous calcifications, years after radiotherapy.
  • The findings underscore the importance of long-term monitoring for patients treated with radiation therapy.
  • Subcutaneous calcification is a potential, albeit uncommon, sequela of radiation exposure.