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Traceless solid-phase synthesis of substituted benzimidazoles via a base-cleavable linker
1Affymax Research Institute, 4001 Miranda Avenue, Palo Alto, California 94304, USA. david_tumelty@affymax.com
Organic Letters
|June 30, 2001
Abstract:
[figure: see text] A solid-phase route to substituted benzimidazoles has been developed using a modified base-labile linker strategy to release the final products in a traceless manner. This approach permits the synthesis of diverse compounds in moderate yields and high purity.