Related Experiment Video
Updated: Oct 5, 2026

Rat Hindlimb Below-Knee Amputation Model and Immediate Targeted Muscle Reinnervation
Published on: May 22, 2026
[Phantom pain after amputation of extremities]
1Arhus Universitetshospital, Arhus Kommunehospital, Dansk Smerteforskningscenter. nikolajsen@dadlnet.dk
Abstract:
Phantom pain is experienced by about 70% of patients following limb amputation. In most patients, both the frequency and the intensity of pain attacks diminish with time, but severe pain persists in about 5-10%. The mechanisms underlying pain in amputees are not fully understood, but factors in both the peripheral and central nervous system play a role. Pain before the amputation seems to increase the risk of phantom pain, but the relation is not simple. Treatment of phantom pain is not successful; a recent study on prevention of the pain with a preoperative epidural blockade showed negative results. The future may reveal new specific drugs for treatment.
More Related Videos
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Blood and Nerve Supply to the Bones
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Somatosensation
Peripheral Artery Disease IV: Nursing Management

