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Published on: April 25, 2014
A giant left ventricular thrombus in a patient with acute myocardial infarction--a case report
1Department of Cardiology, Fukuoka University School of Medicine, Japan.
Insights
A patient with acute myocardial infarction and a giant left ventricular thrombus achieved successful treatment with percutaneous coronary intervention and anticoagulation. The thrombus resolved, and no arterial thromboembolism occurred.
Area of Science:
- Cardiology
- Nephrology
- Vascular Medicine
Background:
- Acute anteroseptal myocardial infarction presents complex challenges, especially with coexisting conditions like nephrotic syndrome.
- Diabetic nephropathy can increase cardiovascular risk and complicate treatment strategies.
Observation:
- A patient presented with acute anteroseptal myocardial infarction and a giant left ventricular apical thrombus.
- The patient also had nephrotic syndrome secondary to diabetic nephropathy.
- Coronary angiography revealed severe stenosis in the left anterior descending artery.
Findings:
- Successful percutaneous transluminal coronary angioplasty and stenting restored coronary blood flow.
- Intravenous heparin followed by warfarin led to the complete resolution of the left ventricular thrombus within 46 days.
- Echocardiography confirmed no arterial thromboembolism during thrombus resolution.
Implications:
- This case highlights the successful management of a large left ventricular thrombus in the context of myocardial infarction and diabetic nephropathy.
- Effective anticoagulation and revascularization are crucial for preventing thromboembolic complications.
- Integrated care addressing both cardiac and renal conditions is essential for optimal patient outcomes.
Abstract:
The authors report a patient with acute anteroseptal myocardial infarction with a giant left ventricular thrombus at the apex. The patient also had nephrotic syndrome due to diabetic nephropathy. Coronary angiography showed 90% stenosis at segment 6 of the left anterior descending coronary artery. Percutaneous transluminal coronary angioplasty and intracoronary stenting were performed on the 30th day, and effective coronary blood flow was obtained. Heparin was injected intravenously for the first 7 days, and warfarin was administered thereafter. The left ventricular thrombus disappeared after 46 days. No evidence of arterial thromboembolism was found during the disappearance of the left ventricular thrombus as determined by echocardiography.
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