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Updated: Aug 4, 2026
14:54
A Controlled Mouse Model for Neonatal Polymicrobial Sepsis
Published on: January 27, 2019
[Risk factors for nosocomial sepsis: a case-control study]
C Fariñas Alvarez1, M Carmen Fariñas, J Llorca
1Cátedra de Medicina Preventiva y Salud Pública Facultad de Medicina. Universidad de Cantabria. Santander. concepcion.farinas@unican.es
Medicina Clinica
|July 7, 2001
Summary
Identifying risk factors for nosocomial sepsis is crucial for prevention. Key predictors include coma, renal failure, and previous infections, alongside intensive care unit (ICU) stays and invasive devices.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
- Hospital Epidemiology
Context:
- Nosocomial sepsis, a significant healthcare-associated infection, poses a major threat to patient safety.
- Understanding its risk factors is essential for developing targeted prevention strategies.
Purpose:
- This study aimed to identify intrinsic and extrinsic risk factors for nosocomial sepsis syndrome.
- Utilizing a case-control design, the research sought to quantify the association of various factors with sepsis development.
Summary:
- A prospective case-control study identified significant risk factors for nosocomial sepsis.
- Intrinsic factors included coma, renal failure, neoplasms, and low serum albumin. Extrinsic factors comprised prior nosocomial infections, intensive care unit (ICU) stay, and indwelling devices like urinary catheters and central lines.
Impact:
- Findings highlight the importance of vigilant monitoring for patients with identified risk factors.
- This research can inform clinical practice and hospital infection control policies to reduce sepsis incidence.
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