Related Experiment Video
Updated: Aug 11, 2026

Longitudinal Intravital Imaging of Brain Tumor Cell Behavior in Response to an Invasive Surgical Biopsy
Published on: May 3, 2019
Inverted pyramidal biopsy
P J Weber1, B R Moody, J A Foster
1Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, USA. daehler@interpoint.net
Abstract:
We describe a biopsy technique that is simple, rapid, and effective for numerous cutaneous lesions. The inverted pyramidal biopsy (IPB) creates an acute geometric tissue defect with an apex located in the dermis. A cosmetically pleasing result, while still providing adequate tissue to render a histologic description and diagnosis, is obtained. The technique can also be employed to remove a host of benign lesions, including dermatofibroma, fibrous papules, and chalazion, among others.

