[Effect of prednisolone on the vascular tonicity of patients with thyrotoxicosis]

In 118 patients suffering from thyrotoxicosis before and after the operation by the method of rheography a study was made of the effect of prednisolone on the stroke and minute volume of the heart, hydraulic resistance of peripheral vessels and the tone of the vessels of extremities. Brief courses of prednisolone treatment (medium doses) before the operation and also after it promoted a more rapid normalization of the mentioned indices. High doses of glucocorticoids prescribed under conditions of a thyrotoxic crisis also influenced the state of the systemic circulation favourably. The data obtained showed that it was expedient to include short courses of low and medium doses of prednisolone into the complex treatment of patients with thyrotoxicosis and in case of developed thyrotoxic crises, to carry out massive hormonal therapy.