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Postirradiation multiple minute digitate porokeratosis
R M Pujol1, E Perez-Losada, X Matias-Guiu
1Department of Dermatology, Hospital del Mar, IMAS, Barcelona, Spain. 93329@imas.imim.es
Journal of Cutaneous Medicine and Surgery
|July 10, 2001
Summary
A rare skin condition, multiple minute digitate hyperkeratoses (MMDH), can develop after radiation therapy. This case suggests MMDH is a distinct radiation-induced disorder within the porokeratosis spectrum.
Area of Science:
- Dermatology
- Oncology
- Radiation Oncology
Background:
- Multiple minute digitate hyperkeratoses (MMDH) are a known post-irradiation skin reaction.
- Previous cases showed lesions confined to the radiation field with specific histopathological features.
Observation:
- A 78-year-old woman developed tiny, filiform, keratotic papules on her chest wall.
- These lesions appeared 13 months after postmastectomy cobalt irradiation for breast cancer.
Findings:
- The observed condition presented as multiple discrete, tiny, filiform, keratotic papules.
- Histopathology revealed a focal column of parakeratosis (cornoid lamella) without a granular layer.
Implications:
- Postirradiation MMDH is a peculiar radiation-induced disorder.
- This condition should be differentiated from other MMDH cases.
- It warrants classification within the spectrum of porokeratosis.