Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endothelial dysfunction in endocrine disease.

T A Abdu1, T Elhadd, M Pfeifer

  • 1Dept of Medicine, School of Postgraduate Medicine, Keele University, Staffordshire, ST4 7QB, Keele, UK.

Trends in Endocrinology and Metabolism: TEM
|July 11, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Whole-genome sequencing reveals two prolonged simultaneous outbreaks involving Pseudomonas aeruginosa high-risk strains ST111 and ST235 with resistance to quaternary ammonium compounds.

The Journal of hospital infection·2024
Same author

[German S1 Guideline Long-/Post-COVID].

Pneumologie (Stuttgart, Germany)·2022
Same author

COVID-19 Lockdown Periods in 2020: Good Maintenance of Metabolic Control in Adults with Type 1 and Type 2 Diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association·2022
Same author

[Statement of the German Society for Pulmonology and Respiratory Medicine Regarding the Regulation to Use FFP and Surgical Masks in the General Population].

Pneumologie (Stuttgart, Germany)·2021
Same author

[S2k Guideline - Recommendations for Inpatient Therapy of Patients with COVID-19].

Pneumologie (Stuttgart, Germany)·2021
Same author

[Weaning in a Pandemic Situation - A Position Paper].

Pneumologie (Stuttgart, Germany)·2020

Endothelial dysfunction is an early cardiovascular disease marker in endocrinopathies. Measuring endothelial function, like flow-mediated dilation (FMD), helps identify at-risk patients and assess treatment effectiveness for cardiovascular disease (CVD).

Area of Science:

  • Endocrinology
  • Cardiovascular Medicine
  • Vascular Biology

Background:

  • Endocrinopathies such as acromegaly, Cushing's syndrome, and thyroid disorders are linked to increased cardiovascular disease (CVD) risk and mortality.
  • Endothelial dysfunction is recognized as an early indicator of CVD, preceding detectable atherosclerotic changes.
  • Assessing endothelial function may enable early identification of at-risk individuals and monitor therapeutic interventions for CVD.

Purpose of the Study:

  • To review the role of endothelial function assessment in endocrinopathies.
  • To highlight the utility of measuring endothelial function for early CVD risk stratification and treatment evaluation.

Main Methods:

  • Noninvasive ultrasound measurement of flow-mediated endothelium-dependent dilation (FMD) in large vessels.

Related Experiment Videos

  • Analysis of serum markers of endothelial dysfunction, including von Willebrand's factor, thrombomodulin, E-selectin, and intercellular adhesion molecule 1.

    • Main Results:

    • Endothelial dysfunction is a common finding in various endocrinopathies associated with CVD.
    • Serum markers of endothelial dysfunction correlate inversely with FMD measurements.
    • FMD and serum markers show potential for monitoring treatment efficacy in reducing CVD risk.

    Conclusions:

    • Endothelial function assessment, particularly FMD, is a valuable tool for early CVD risk identification in patients with endocrinopathies.
    • Serum biomarkers can complement FMD measurements in evaluating treatment responses and long-term CVD outcomes.