Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vascular tissue engineering.

R M Nerem1, D Seliktar

  • 1Georgia Tech/Emory Center for the Engineering of Living Tissues, Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, USA. robert.nerem@ibb.gatech.edu

Annual Review of Biomedical Engineering
|July 12, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel extrusion-based 3D bioprinting system for skeletal muscle tissue engineering.

Biofabrication·2023
Same author

PlGF-MMP9-engineered iPS cells supported on a PEG-fibrinogen hydrogel scaffold possess an enhanced capacity to repair damaged myocardium.

Cell death & disease·2014
Same author

Tissue engineering: from biology to biological substitutes.

Tissue engineering·2009
Same author

Tissue engineering: from basic science to products: a preface.

Tissue engineering·2009
Same author

The role of fluid mechanics in atherogenesis.

Journal of biomechanical engineering·2009
Same author

Bioengineered tissues: the science, the technology, and the industry.

Orthodontics & craniofacial research·2005

Tissue-engineered blood vessel substitutes are advancing cardiovascular tissue engineering. This review covers key methods like cell-seeded gels and scaffolds, highlighting progress and future challenges.

Area of Science:

  • Cardiovascular Tissue Engineering
  • Biomaterials Science
  • Regenerative Medicine

Background:

  • Significant research in cardiovascular tissue engineering over two decades has focused on developing functional blood vessel substitutes.
  • Existing approaches aim to create viable alternatives to natural blood vessels for various medical applications.

Purpose of the Study:

  • To review recent advancements in tissue-engineered blood vessel substitute development.
  • To analyze core technologies and construct development strategies.
  • To discuss benefits, drawbacks, and common themes across different methodologies.

Main Methods:

  • Review of methodologies including cell-seeded collagen gels, biodegradable synthetic polymer scaffolds, cell self-assembly, and acellular techniques.

Related Experiment Videos

  • Focus on core technologies and construct development.
  • Analysis of specific examples to illustrate methodology performance.

    • Main Results:

    • Multiple techniques have emerged for creating biologically functional blood vessel replacements.
    • Each method presents unique advantages and limitations.
    • Common themes and challenges in construct development are identified.

    Conclusions:

    • Continued innovation in tissue engineering is crucial for advancing cardiovascular therapies.
    • Addressing current limitations will pave the way for more effective blood vessel substitutes.
    • Future research should focus on overcoming key challenges in the field.