Related Experiment Video

Updated: Oct 5, 2026

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
12:57

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

Transgenic studies of the influence of the PrP structure on TSE diseases

E A Asante1, J Collinge

  • 1MRC Prion Unit and Department of Neurogenetics, Imperial College School of Medicine at St. Mary's, London W2 1PG, United Kingdom.

Advances in Protein Chemistry
|July 13, 2001
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay
11:41

Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay

Published on: March 10, 2015

Retroviral Transduction of Bone Marrow Progenitor Cells to Generate T-cell Receptor Retrogenic Mice
09:08

Retroviral Transduction of Bone Marrow Progenitor Cells to Generate T-cell Receptor Retrogenic Mice

Published on: July 11, 2016

Related Experiment Videos

Last Updated: Oct 5, 2026

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
12:57

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay
11:41

Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay

Published on: March 10, 2015

Retroviral Transduction of Bone Marrow Progenitor Cells to Generate T-cell Receptor Retrogenic Mice
09:08

Retroviral Transduction of Bone Marrow Progenitor Cells to Generate T-cell Receptor Retrogenic Mice

Published on: July 11, 2016

Related Concept Videos

Transgenic Organisms01:26

Transgenic Organisms

Transgenic organisms are genetically engineered to carry transgenes—genes from a different species—as part of their genome. The transgene may either be a different version of one of the organism’s genes or a gene that does not exist in their genome. Transgenes are usually generated by recombinant DNA and DNA cloning techniques. Transgenic bacteria, plants, and animals allow scientists to address biological queries and design practical solutions.Creating a Transgenic OrganismScientists begin the...
Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...

Articles linked to this work by shared authors, journal, and citation graph.

Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series.

Molecular psychiatry·2018

Cultural factors that affected the spatial and temporal epidemiology of kuru.

Royal Society open science·2017

Genome-wide association study of behavioural and psychiatric features in human prion disease.

Translational psychiatry·2015

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

Nature genetics·2013

Multiparameter MR imaging in the 6-OPRI variant of inherited prion disease.

AJNR. American journal of neuroradiology·2013

PRION-1 scales analysis supports use of functional outcome measures in prion disease.

Neurology·2011

Regulation of Rho guanine nucleotide exchange factors by G proteins.

Advances in protein chemistry·2007

Kinetic analysis of G protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells.

Advances in protein chemistry·2007

Activation of G protein-coupled receptors.

Advances in protein chemistry·2007

Some mechanistic insights into GPCR activation from detergent-solubilized ternary complexes on beads.

Advances in protein chemistry·2007

How do receptors activate G proteins?

Advances in protein chemistry·2007

Structural basis of effector regulation and signal termination in heterotrimeric Galpha proteins.

Advances in protein chemistry·2007

A murine model of amyloid enhanced tauopathy: progressive changes in tau pathology and behavior.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Integrating deep learning model for precision design of MERS antibodies with augmented affinity against SARS-CoV-2.

Journal of biomolecular structure & dynamics·2026

Impact of the physico-chemical properties of surface-initiated polymer brushes on siRNA binding and transfection efficiency.

Biomaterials science·2026

Dose effect of bilateral transcranial magnetic stimulation for depression and anxiety in a real-world clinical setting.

Journal of mood and anxiety disorders·2026

Real-World Outcomes of Venetoclax and Azacitidine in Hospitalized Patients With Acute Myeloid Leukemia: A Retrospective Study at a Tertiary Care Center.

Advances in hematology·2026

Clinical immunogenicity in rAAV gene therapy: Insights and implications.

Molecular therapy. Advances·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us