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Single-Molecule Imaging of Nuclear Transport
12:13

Single-Molecule Imaging of Nuclear Transport

Published on: June 9, 2010

Biophysical characterization of interactions involving importin-alpha during nuclear import

B Catimel1, T Teh, M R Fontes

  • 1Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Victoria 3050, Australia.

The Journal of Biological Chemistry
|July 13, 2001
PubMed
Summary

Nuclear import proteins bind importin-alpha, which is regulated by an autoinhibitory domain. Importin-beta binding enhances NLS binding, facilitating nuclear transport regulation.

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