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Disseminated pagetoid reticulosis: plaques and tumoral lesions occurring simultaneously in the same patient
G Bükülmez1, N Atakan, M Taşkin
1Hacettepe University Faculty of Medicine Department of Dermatology, Sihhiye, Ankara, Turkey. bukulmez@hacettepe.edu.tr
Abstract:
Disseminated pagetoid reticulosis is considered to have a poor prognosis. Some authors regard this disease as an epidermotropic type of mycosis fungoides rather than a distinct entity. We report the case of an 83-year-old woman with disseminated pagetoid reticulosis who subsequently developed tumoral lesions and died soon after the appearance of these tumours. Our case is in agreement with findings that disseminated pagetoid reticulosis has an aggressive clinical behaviour.
Insights
Disseminated pagetoid reticulosis, a skin condition, often indicates a poor prognosis. This case report confirms its aggressive nature, progressing to fatal tumoral lesions.
Area of Science:
- Dermatology
- Oncology
Background:
- Disseminated pagetoid reticulosis (DPR) is a rare cutaneous condition.
- Its classification remains debated, with some considering it a variant of mycosis fungoides.
Observation:
- An 83-year-old female patient presented with disseminated pagetoid reticulosis.
- The patient subsequently developed aggressive tumoral lesions.
Findings:
- The patient's condition rapidly progressed, leading to death shortly after the onset of tumoral lesions.
- This case supports the view that DPR exhibits aggressive clinical behavior.
Implications:
- Disseminated pagetoid reticulosis requires prompt recognition and management due to its poor prognosis.
- Further research may clarify the relationship between DPR and mycosis fungoides.