Related Experiment Video

Updated: Aug 2, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Impact of Genetic potential and prematurity on growth outcomes

L L Lindeke1, C D Shell, M M Mills

  • 1School of Nursing, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA. linde001@tc.umn.edu

MCN. the American Journal of Maternal Child Nursing
|July 17, 2001
PubMed

Insights

Children born prematurely often achieve normal growth by school age, with maternal height being a key predictor. Close monitoring of growth is recommended for children born prematurely.

Area of Science:

  • Pediatric Growth and Development
  • Neonatal Follow-up
  • Genetics and Growth

Background:

  • Premature birth can impact childhood growth trajectories.
  • Understanding factors influencing catch-up growth is crucial for long-term outcomes.

Purpose of the Study:

  • To investigate the relationship between genetic potential and catch-up growth in school-aged children born prematurely.
  • To assess growth and body composition in relation to birthweight categories.

Main Methods:

  • Descriptive correlational study of 45 children born prematurely, categorized by birthweight (low, very low, extremely low).
  • Comparison of height and weight to normal birthweight norms.
  • Correlation of school-age growth and parental heights.

Main Results:

  • All birthweight groups achieved growth within normal ranges by school age.
  • Extremely low birthweight group showed growth in the lower end of the normal range.
  • Maternal height was the strongest predictor of children's height at 8-10 years.

Conclusions:

  • Many children overcome adverse effects of prematurity on growth.
  • Close monitoring of growth using appropriate grids and prematurity correction is essential.
  • Reassurance for parents and providers regarding catch-up growth potential.
Abstract

More Related Videos

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis06:19

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

Published on: January 7, 2018

Concurrent Collection of Fetal Murine Brain and Serum to Assess Effects of Maternal Diet on Nutrition and Neurodevelopment in Neurofibromatosis Type 105:44

Concurrent Collection of Fetal Murine Brain and Serum to Assess Effects of Maternal Diet on Nutrition and Neurodevelopment in Neurofibromatosis Type 1

Published on: May 17, 2024

Related Concept Videos

Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience, such as differences...
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Gene-Environment Interactions01:20

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
Biological Influences on Intelligence01:30

Biological Influences on Intelligence

Intelligence is often thought to be linked to brain size, but the relationship is more complex than that. While brain size does correlate modestly with some abilities, like verbal skills, the connection is weaker for others, such as spatial reasoning. Other factors, like brain structure, also play crucial roles. For instance, despite Einstein's smaller-than-average brain, his parietal cortex, which is involved in spatial reasoning, was 15% wider, suggesting that neural density might matter more...