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Updated: Aug 2, 2026

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A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training
Published on: January 29, 2017
[Effect of marinobufagenin on the primary reinforcing effect of ethanol]
V A Kashkin1, N A Patkina, A Ia Bagrov
1St. Petersburg I. P. Pavlov State Medical University, 197022, St. Petersburg, Leo Tolstoy St., 6/8, Russia.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
|July 17, 2001
Abstract:
Intraperitoneal administration of marinobufagenin resulted in a reliable and dose-dependent suppression of ethanol self-administration in drug- and experimentally naive DBA/2 mice. The findings suggest that Na/K-ATPase contributes to both mediation of the ethanol reinforcing properties and the mood regulation.

