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[Immunophenotype characteristics of blood lymphocytes in patients with lymphogranulomatosis]
The blood lymphocyte immunophenotype was studied in patients with lymphogranulomatosis including those having been exposed to the Chernobyl spectrum radionuclide radiation in the doses up to 75 sGy. It is shown that in both groups of patients, there tends to be a decline in indices for T- and EK-cell immunity, that comes to be the most apparent in radiation-associated lymphogranulomatosis. The data obtained provide scientific explanation of more aggressive course of the disease in such patients and of difficulty in treatment.
The blood lymphocyte immunophenotype was studied in patients with lymphogranulomatosis including those having been exposed to the Chernobyl spectrum radionuclide radiation in the doses up to 75 sGy. It is shown that in both groups of patients, there tends to be a decline in indices for T- and EK-cell immunity, that comes to be the most apparent in radiation-associated lymphogranulomatosis. The data obtained provide scientific explanation of more aggressive course of the disease in such patients and of difficulty in treatment.