Related Experiment Video

Updated: Oct 5, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Diffusion-weighted imaging in moyamoya disease

T B Soman1, M Takeoka, E C Dooling

  • 1Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, USA. teestas@yahoo.com

Journal of Child Neurology
|July 17, 2001
PubMed

Insights

Diffusion-weighted imaging (DWI) helps track new brain infarcts in children with moyamoya disease. DWI distinguishes acute lesions, aiding in monitoring disease progression and treatment effectiveness.

Area of Science:

  • Neurology
  • Radiology
  • Pediatric Neurology

Background:

  • Moyamoya disease involves progressive stenosis of intracranial arteries, leading to recurrent ischemic strokes.
  • Pediatric moyamoya disease presents with significant neurological deficits due to these ischemic events.

Observation:

  • Serial diffusion-weighted imaging (DWI) studies were performed on a 4-year-old patient with moyamoya disease and multiple hemispheric infarcts.
  • New infarcts appeared as hyperintense (bright) lesions on DWI, while older infarcts were not hyperintense on DWI.

Findings:

  • DWI effectively identified acute ischemic lesions, differentiating them from pre-existing infarcts.
  • The imaging modality aided in assessing the extent and age of brain infarcts.
  • Correlation between new DWI findings and clinical presentation was established.

Implications:

  • Diffusion-weighted imaging is a valuable tool for monitoring the clinical course of pediatric moyamoya disease.
  • DWI assists in the early detection of new infarcts, prompting timely clinical correlation and management adjustments.
  • This technique enhances the understanding and management of cerebrovascular disease in children.

More Related Videos

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia09:59

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

Middle Cerebral Artery Occlusion Allowing Reperfusion via Common Carotid Artery Repair in Mice06:59

Middle Cerebral Artery Occlusion Allowing Reperfusion via Common Carotid Artery Repair in Mice

Published on: January 23, 2019

Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...