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Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae)
1School of Pharmacy, The Robert Gordon University, Schoolhill, AB10 1FR, Scotland, Aberdeen, UK. s.sarker@rgu.ac.uk
Phytochemistry
|July 17, 2001
Abstract:
Preparative RP-HPLC analysis of a methanol extract of the seeds of Centaurea cyanus afforded four indole alkaloids: moschamine, cis-moschamine, centcyamine and cis-centcyamine, the latter two being new natural products. Structures of these compounds were elucidated by comprehensive spectroscopic analyses. General toxicity of the isolates was determined by Brine Shrimp Lethality bioassay.