Related Experiment Video
Updated: Aug 14, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
Published on: July 29, 2014
Opioid analgesic drugs in older people
1Pain Management Center, Department of Anesthesiology, University of Utah, Salt Lake City, Utah 84108, USA.
Abstract:
Many studies have corroborated the finding that older patients in all clinical settings are at risk for insufficient assessment and inadequate management of pain. Opioid analgesics can greatly improve the quality of life and functional capacities of older patients with moderate to severe pain that is not responsive to other therapies; however, these agents are underused in this population. To improve the care of older patients, clinicians must develop expertise in appropriate indications, pharmacologic properties, drug-disease and drug-drug interactions, and ongoing monitoring of opioid analgesic therapy.
Related Concept Videos
Analgesia and Pain Management
Opioid Analgesics: Morphine and Other Natural Cogeners
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacodynamics in Geriatric Patients: Effects of Age

