Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Photodermatosis induced by hydroxychloroquine: 4 cases].

I Métayer1, X Balguerie, P Courville

  • 1Clinique Dermatologique, Hôpital Charles Nicole, 1, rue de Germont, 76031 Rouen Cedex.

Annales De Dermatologie Et De Venereologie
|July 19, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mammary and extramammary diffuse dermal angiomatosis: a case series and review of the literature.

Annales de dermatologie et de venereologie·2025
Same author

Epidemiological changes in cutaneous lymphomas: an analysis of 8593 patients from the French Cutaneous Lymphoma Registry.

The British journal of dermatology·2020
Same author

Locoregional nodal extension does not impair prognosis of primary cutaneous anaplastic lymphomas.

The British journal of dermatology·2020
Same author

[Myocardial infarction in a patient on immunoglobulin therapy].

Annales de dermatologie et de venereologie·2020
Same author

Sensitivity to change and correlation between the autoimmune bullous disease quality-of-life questionnaires ABQOL and TABQOL, and objective severity scores.

The British journal of dermatology·2020
Same author

Expert recommendations for the management of autoimmune bullous diseases during the COVID-19 pandemic.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020
Same journal

2024 guidelines (S3) for the therapeutic management of patients with genital herpes.

Annales de dermatologie et de venereologie·2026
Same journal

Topical JAK inhibitors in the lichen planus spectrum: a systematic review.

Annales de dermatologie et de venereologie·2026
Same journal

2024 recommendations for the therapeutic management of anogenital warts.

Annales de dermatologie et de venereologie·2026
Same journal

Successful use of thalidomide in treating metastatic Crohn's disease.

Annales de dermatologie et de venereologie·2026
Same journal

Multiple cutaneous juvenile xanthogranuloma: a monocentric study.

Annales de dermatologie et de venereologie·2026
Same journal

Cartilage-hair-hypoplasia associated with granulomatosis induced by rubella vaccine.

Annales de dermatologie et de venereologie·2026
See all related articles

Hydroxychloroquine, an antimalarial drug, can rarely cause photodermatosis, leading to light-sensitive skin reactions. Discontinuation of hydroxychloroquine typically resolves these adverse effects.

Area of Science:

  • Dermatology
  • Pharmacology
  • Toxicology

Context:

  • Hydroxychloroquine (HCQ) is widely used in dermatology for its photo-protective properties.
  • However, rare instances of photosensitivity reactions to HCQ have been documented.
  • Understanding these adverse effects is crucial for patient safety and effective treatment.

Purpose:

  • To report four cases of photodermatosis induced by hydroxychloroquine.
  • To analyze the clinical presentation, causative factors, and outcomes of these reactions.
  • To differentiate HCQ-induced photodermatosis from underlying photodermatoses.

Summary:

  • Four patients developed photolocalized eruptions after initiating hydroxychloroquine, with onset ranging from 6 days to 10 weeks.
  • Minimal erythemal dose testing showed decreased tolerance to UV radiation during eruptions, normalizing after HCQ cessation.

Related Experiment Videos

  • Hydroxychloroquine was deemed the primary cause in three cases; one case involved co-imputability with other medications. All patients improved after discontinuing HCQ.

    • Impact:

    • This study highlights the rare but significant risk of photosensitivity reactions associated with hydroxychloroquine.
    • It emphasizes the importance of considering drug-induced photodermatosis in patients presenting with light-sensitive eruptions.
    • The findings aid clinicians in differential diagnosis and managing adverse reactions to hydroxychloroquine.