Related Experiment Video

Updated: Oct 5, 2026

Quantification of Atherosclerosis in Mice
06:59

Quantification of Atherosclerosis in Mice

Published on: June 12, 2019

[Atherosclerotic changes in the aorta of patients with ischemic and hemorrhagic stroke]

T Mendel1, J Popow, D Ryglewicz

  • 1II Kliniki Neurologicznej, Instytutu Psychiatrii i Neurologii w Warszawie.

Neurologia I Neurochirurgia Polska
|July 24, 2001
PubMed

Insights

Atherosclerotic lesions in the aortic arch were more common in ischemic stroke patients than hemorrhagic stroke patients. Advanced aortic atherosclerosis occurred similarly in both stroke types.

Area of Science:

  • Neurology
  • Cardiovascular Pathology
  • Vascular Biology

Context:

  • Stroke is a leading cause of death and disability worldwide.
  • Atherosclerosis is a major risk factor for stroke.
  • Understanding the distribution of atherosclerotic lesions in different aortic segments is crucial for stroke risk stratification.

Purpose:

  • To compare the prevalence and severity of atherosclerotic lesions in the aortic arch, thoracic aorta, and abdominal aorta between patients who died from ischemic stroke and hemorrhagic stroke.

Summary:

  • This clinico-pathological study analyzed 207 patients who died after stroke.
  • Moderate atherosclerotic lesions in the aortic arch were more frequent in ischemic stroke cases compared to hemorrhagic stroke.
  • Advanced atherosclerotic lesions showed similar frequencies in the thoracic and abdominal aorta for both ischemic and hemorrhagic stroke patients.

Impact:

  • Findings suggest that aortic arch atherosclerosis may play a differential role in ischemic versus hemorrhagic stroke.
  • This research could inform targeted prevention strategies for different stroke subtypes.
  • Highlights the importance of detailed vascular pathology assessment in stroke mortality studies.

More Related Videos

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus06:43

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus

Published on: December 7, 2013

Isolation and Analysis of Aortic Arch and Root Lesions in an Atherosclerotic Mouse Model07:49

Isolation and Analysis of Aortic Arch and Root Lesions in an Atherosclerotic Mouse Model

Published on: February 14, 2025

Related Concept Videos

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Atherosclerosis IV: Nursing Management01:23

Atherosclerosis IV: Nursing Management

Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...