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[Value of complementary medicine exemplified by rose-hips]
1Institut für Sozialmedizin und Epidemiologie, Universitätsklinikum Charité, Humboldt-Universität zu Berlin.
Gesundheitswesen (Bundesverband Der Arzte Des Offentlichen Gesundheitsdienstes (Germany))
|July 27, 2001
Summary
Rose-hip extract, derived from wild roses, shows anti-inflammatory effects. Clinical studies suggest it may reduce osteoarthritis symptoms and improve joint function.
Area of Science:
- Phytochemistry
- Pharmacology
- Clinical Medicine
Context:
- Rose-hip (Rosa canina) is a natural remedy with a history of traditional use.
- Osteoarthritis (OA) is a degenerative joint disease with limited treatment options.
- Inflammation plays a key role in the pathogenesis and symptoms of OA.
Purpose:
- To investigate the anti-inflammatory properties and clinical efficacy of rose-hip extract in osteoarthritis.
- To evaluate the effects of rose-hip on inflammatory markers and physical symptoms in OA patients.
Summary:
- Laboratory studies demonstrate rose-hip extract's ability to inhibit lipid oxidation and modulate inflammatory cell activity (leukocyte chemotaxis and chemiluminescence).
- Clinical trials indicate a reduction in C-reactive protein (CRP) and creatinine levels in healthy subjects and OA patients receiving rose-hip treatment.
- Patients with osteoarthritis reported decreased physical symptoms, pain reduction, and improved hip flexion in a randomized controlled trial.
Impact:
- Rose-hip extract exhibits anti-inflammatory properties, suggesting its potential as a natural therapeutic agent for osteoarthritis management.
- Further research is needed to identify the specific active components, such as flavonoids, responsible for the observed therapeutic effects.