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Updated: Aug 12, 2026

Expression Analysis of Mammalian Linker-histone Subtypes
Published on: March 19, 2012
Influence of linker histone H1 on chromatin remodeling
1Department of Cell Biology, University of Massachusetts Medical School, Worcester 01655, USA. david.hill@umassmed.edu
Abstract:
Chromatin-remodeling complexes have been a central area of focus for research dealing with accessing cellular DNA sequestered in chromatin. Although the linker histone H1 plays a major role in promoting and maintaining higher-order chromatin structure, it has been noticeably absent from assays utilizing chromatin-remodeling enzymes. This review focuses on two ATP-dependent chromatin-remodeling complexes, Drosophila ISWI and mammalian SWI/SNF, that have been assayed using chromatin templates containing histone H1.
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