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Synthesis of a non-natural T-antigen containing glycosphingolipid
Carbohydrate Letters
|July 27, 2001
Abstract:
A non natural glycosphingolipid containing the mucin derived, cancer associated disaccharide moiety Galbeta1-->3GalNAc, the T-antigen, alpha linked to a ceramide, has been synthesised via the protected disaccharide glycosyl trichloroacetimidate. The product has potential as a cancer vaccine.