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A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine
F Taraballi1, L Russo, C Battocchio
1Pain Therapy Service, Fondazione IRCCS Policlinico San Matteo, via Golgi, 19-27100 Pavia, Italy.
Organic & Biomolecular Chemistry
|May 20, 2014
Abstract:
A new approach for tethering of bioactive molecules via arginine is proposed and validated on collagen 2D matrices. The method involves the introduction of a methyl ketone on arginine side-chains, followed by reaction with model alkoxyamino derivatives.
