Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anal Carcinoma.

Eric J. Szilagy1, Asim Farid

  • 1Division of Colon and Rectal Surgery, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.

Current Treatment Options in Gastroenterology
|July 27, 2001
PubMed
Summary

Anorectal cancer, though visible, is often diagnosed late. Modern treatment combines chemotherapy (fluorouracil, mitomycin) and radiation, with surgery reserved for specific cases like residual or recurrent disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determining the depositional pattern by resistivity-seismic inversion for the aquifer system of Maira area, Pakistan.

Environmental monitoring and assessment·2011
Same author

Diversion Colitis.

Current treatment options in gastroenterology·2001
See all related articles

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Anal cancer is a rare malignancy.
  • Diagnosis is frequently delayed despite anatomical accessibility.
  • Treatment paradigms have shifted significantly over time.

Purpose of the Study:

  • To summarize the current understanding of anal carcinoma diagnosis and treatment.
  • To outline the evolution of therapeutic strategies for anal cancer.

Main Methods:

  • Review of current treatment protocols for anal carcinoma.
  • Description of the roles of surgery, chemotherapy, and radiation therapy.
  • Identification of indications for different surgical approaches.

Main Results:

  • Chemoradiation (fluorouracil, mitomycin, and megavoltage radiation) is the primary treatment modality.
  • Local surgical excision is suitable for early-stage disease (carcinoma in situ, microinvasive lesions).
  • Radical resection is reserved for persistent or recurring anal cancer post-chemoradiation.

Conclusions:

  • Anal cancer management has transitioned to a multimodality approach.
  • Tailored surgical interventions are crucial for specific patient subgroups.
  • Effective treatment relies on integrating chemotherapy, radiation, and surgery.

Related Experiment Videos