Related Experiment Video

Updated: Jul 15, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Trend in childhood tuberculosis in Benin City, Nigeria

M O Ibadin1, O Oviawe

  • 1Department of Child Health, University of Benin Teaching Hospital, Benin City, Nigeria.

Annals of Tropical Paediatrics
|July 27, 2001
PubMed

Insights

Childhood tuberculosis cases rose significantly from 1981 to 1995, with a shift towards adult-type disease. Increased severity, including hemoptysis and finger clubbing, was observed in pediatric tuberculosis patients.

Area of Science:

  • Pediatric Medicine
  • Infectious Diseases
  • Epidemiology

Background:

  • Childhood tuberculosis presents unique diagnostic and management challenges.
  • Understanding temporal trends in pediatric tuberculosis is crucial for public health interventions.

Purpose of the Study:

  • To analyze the trends and clinical patterns of childhood tuberculosis over a 15-year period.
  • To identify changes in disease severity and presentation in pediatric tuberculosis cases.

Main Methods:

  • Retrospective review of case records of children diagnosed with tuberculosis.
  • Analysis of data from January 1981 to December 1995 at a university teaching hospital.
  • Statistical evaluation of case proportions, clinical patterns, and disease severity indicators.

Main Results:

  • Tuberculosis accounted for 11.6% of pediatric medical cases, with a steady increase in proportion from 6.9% to 22.1% over the study period.
  • A shift towards adult-type tuberculosis, characterized by disseminated and cavitating lesions, was observed.
  • Disease severity increased, with hemoptysis rising from 1.6% to 14.2% and finger clubbing from 1.6% to 18.2%.

Conclusions:

  • Childhood tuberculosis trends show a concerning increase and a shift towards more severe, adult-like presentations.
  • Factors such as malnutrition, adult tuberculosis prevalence, and HIV/AIDS may contribute to these observed trends.
  • Public health strategies must address these evolving patterns in pediatric tuberculosis.

More Related Videos

A Tuberculosis Molecular Bacterial Load Assay (TB-MBLA)10:41

A Tuberculosis Molecular Bacterial Load Assay (TB-MBLA)

Published on: April 30, 2020

Micro-Colony Forming Unit Assay for Efficacy Evaluation of Vaccines Against Tuberculosis06:26

Micro-Colony Forming Unit Assay for Efficacy Evaluation of Vaccines Against Tuberculosis

Published on: July 28, 2023

Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...