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Bilateral corneal involvement in epidermolysis bullosa acquisita
P E Dantas1, M C Nishiwaki-Dantas, M H Seguim
1Department of Ophthalmology, Santa Casa Hospital, São Paulo, Brazil. speyecare@originet.com.br
Purpose:
To report clinical and laboratory findings of bilateral corneal involvement in a patient with epidermolysis bullosa acquisita.
Methods:
A 25-year-old man with a history of progressive and painless loss of vision in both eyes presented to our service with bilateral corneal involvement: peripheral corneal perforation in one eye and advanced corneal thinning in the other eye. There was concomitant dermatologic bullous disease. Clinical and laboratory exams were analyzed.
Results:
The patient was diagnosed as having epidermolysis bullosa acquisita. Therapeutic corneal patch graft and conjunctival resection with cryotherapy were done, with satisfactory results.
Conclusion:
Bilateral corneal involvement in epidermolysis bullosa acquisita is described. To the best of our knowledge, this is the first description of such a case. Surgical management of the ocular findings associated with systemic therapy with colchicine seems to be a good therapeutic option in the management of this defying disease.