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Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
Morbidity in electroconvulsive therapy
1Département d'Anesthésie-Réanimation, CHU Dupuytren, 87042 Limoges Cédex, France.
Background And Objective:
To assess retrospectively the complications and morbidity of electroconvulsive therapy.
Methods:
Complications occurring in 75 patients during 612 electroconvulsive therapy procedures under propofol anaesthesia were reviewed by data analysis.
Results:
At least one complication occurred in 51 patients (68%) during the course of their treatment. Among these complications, 12 were potentially life-threatening: one patient developed angina pectoris, another aspiration pneumopathy, there were two incidences of bronchospasm, three hypoxic episodes (SpO2 < 92% with FiO2=1) and five severe episodes of laryngospasm which caused hypoxia. Twenty-five patients (33%) were confused for more than 2 h after the electroconvulsive therapy. Confusion recurred in 10 patients (13%) after several sessions of electroconvulsive treatment. Six patients had a traumatic complication, with one requiring surgery.
Conclusion:
Our results, compared with other studies, suggest that electroconvulsive therapy is not a low-risk procedure, with a particularly high rate of respiratory complications that may have been previously overlooked. Therefore, ambulatory anaesthesia may not be appropriate on a regular basis for most of these patients.
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