Related Experiment Video
Updated: Aug 4, 2026

06:35
Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
Renal cyst causing afferent loop obstruction and acute pancreatitis
The American Surgeon
|July 1, 1975
Summary
A right renal cyst caused afferent loop obstruction, leading to acute pancreatitis. Surgical intervention successfully relieved the obstruction by resecting the cyst wall and repositioning the duodenal loop.
Area of Science:
- Nephrology
- Gastroenterology
- Surgical Pathology
Background:
- Afferent loop obstruction is a rare complication following certain surgical procedures.
- Renal cysts can, in rare instances, cause extrinsic compression of adjacent structures.
- Acute pancreatitis can manifest due to various etiologies, including mechanical obstruction.
Purpose of the Study:
- To describe a unique case of acute pancreatitis secondary to afferent loop obstruction.
- To highlight the role of a renal cyst as an unusual cause of duodenal compression.
- To present the successful surgical management of this rare condition.
Main Methods:
- Case report detailing clinical presentation, diagnostic workup, and surgical intervention.
- Review of relevant literature on renal cysts and afferent loop obstruction.
- Surgical resection of the extrinsic portion of the renal cyst wall and duodenal loop mobilization.
Main Results:
- The patient presented with symptoms consistent with acute pancreatitis.
- Intraoperative findings confirmed afferent loop obstruction due to a right renal cyst.
- Successful surgical relief of the obstruction was achieved with no immediate complications.
Conclusions:
- Right renal cysts can cause significant extrinsic compression leading to afferent loop obstruction and acute pancreatitis.
- Surgical management, including cyst wall resection and duodenal mobilization, is effective in resolving this condition.
- This case underscores the importance of considering extraluminal causes for gastrointestinal obstruction.
Related Concept Videos
Acute Pancreatitis I: Introduction
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis I: Introduction
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pancreatitis I: Introduction
Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
Acute Pancreatitis II: Pathophysiology
The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Chronic Pancreatitis I: Introduction
Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis II: Pathophysiology
Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...

